ScreenClust 1.1

ScreenClust by Corbett Life Science (a QIAGEN company) is an add-on analysis tool designed to turn High-Resolution Melt (HRM) data into clear, objective genotype or variant calls—without the need for labeled probes. Built for the Rotor-Gene platform, ScreenClust applies multivariate analysis and clustering algorithms to HRM curves to automatically group samples, quantify confidence, and highlight outliers, streamlining high-throughput screening and assay development.

Key features and benefits:

• Unsupervised clustering of HRM profiles for rapid, objective genotype calling
• Confidence scores for each assignment, with automatic outlier and replicate handling
• Intuitive visualizations (including PCA-style plots) to review cluster separation and data quality
• Works with Rotor-Gene HRM runs and integrates into existing workflows
• Exportable results for downstream analysis and reporting
• Ideal for SNP genotyping, mutation scanning, methylation studies, and screening applications

With ScreenClust, laboratories can reduce manual interpretation, increase reproducibility, and accelerate decision-making in HRM-based assays.

ScreenClust is developed by Corbett Life Science, a QIAGEN Company.. The most popular version of this product among our users is 1.1. The name of the program executable file is ScreenClust.exe.